Renovations of the buildings resulted in the opening of the Drury Plaza Hotel in 2000. The 370-room hotel has a number of room types, including two-room suites. Many rooms have spectacular views of the Arch, Mississippi River, and Busch Stadium. Other hotel amenities include a business center, meeting rooms, two restaurants, 225 indoor parking spaces, and an indoor swimming pool and exercise room.

The renovation is impressive. Original ornamentation in the lobby of the Fur Exchange that had been destroyed or covered over was restored. Granite and marble were imported to cover lobby floors and support columns. The Thomas Jefferson building was given a new brick exterior to help it blend visually with the Fur Exchange building, whose damaged exterior was also restored.